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N1090000

Nizatidine

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

N-{2-[2-(N,N-Dimethylaminomethyl)-4-thiazolylmethylthio]ethyl}-N′-methyl-2-nitro-1,1-ethenediamine

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About This Item

Empirical Formula (Hill Notation):
C12H21N5O2S2
CAS Number:
Molecular Weight:
331.46
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

nizatidine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C12H21N5O2S2/c1-13-11(6-17(18)19)14-4-5-20-8-10-9-21-12(15-10)7-16(2)3/h6,9,13-14H,4-5,7-8H2,1-3H3/b11-6+

InChI key

SGXXNSQHWDMGGP-IZZDOVSWSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Nizatidine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Richard W McCallum et al.
The American journal of the medical sciences, 340(4), 259-263 (2010-10-01)
The aim of the study is to test whether nizatidine delivered via a unique bimodal pulsatile-controlled release system, nizatidine controlled release (CR), accelerates gastric emptying in patients with gastroesophageal reflux disease (GERD). Combined data were analyzed on 39 patients with
Rasha M Youssef
Journal of AOAC International, 91(1), 73-82 (2008-04-02)
Four new selective, precise, and accurate methods are described for the determination of nizatidine (NIZ) in the presence of its sulfoxide derivative in both the raw material and pharmaceutical preparations. Method A is based on zero-order (0D), first-derivative (1D), and
M Apostu et al.
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 112(3), 856-859 (2008-07-01)
PVC matrix membrane selective electrodes for ranitidine, nizatidine and famotidine, based on sparingly soluble complexes, were prepared and characterized. The optimum functional pH range, response time, selectivity and lifetime were determined for each of the built electrodes. The linear range
K R DeVault et al.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 20(5), 411-415 (2007-09-01)
Several studies suggest that older adults with gastroesophageal reflux disease (GERD) are more likely to develop complications, including erosive esophagitis, but it is unclear whether erosive esophagitis is more difficult to treat in older patients. The purpose of this study
Tsuyoshi Kasama et al.
Modern rheumatology, 18(5), 455-459 (2008-05-15)
In Sjögren's syndrome (SS), oral dryness (xerostomia) is frequently the most bothersome symptom. An H2 histamine receptor antagonist is often administered to SS patients to treat associated superficial gastritis. The aim of the present study was to assess the ability

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