1.08197

Tabletting aid K (cellulose powder)

EMPROVE^® ESSENTIAL, Ph. Eur., BP, JP, NF

• Synonym(s): Tabletting aid K (cellulose powder)
• Linear Formula: (C₆H₁₀O₅)_n
• CAS Number: 9004-34-6
• MDL number: MFCD00081512
• UNSPSC Code: 12352201
• EC Index Number: 232-674-9

Properties

• Agency: BP; JP; NF; Ph. Eur.
• Quality Level: 500
• product line: EMPROVE^® ESSENTIAL
• form: fine powder
• autoignition temp.: 232 °C
• particle size: (see specification)
• pH: 5-7.5 (20 °C, 100 g/L in H₂O, slurry)
• transition temp: flash point 260 °C
• density: 1.5 g/cm³ at 20 °C
• application(s): pharmaceutical; solid formulation
• storage temp.: 15-25°C
• SMILES string: O1[C@H](C(C(C(C1CO)O)O)O)O[C@@H]2C(OC(C(C2O)O)O)CO
• InChI: 1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3?,4?,5?,6?,7?,8?,9?,10-,11?,12+/m1/s1
• InChI key: GUBGYTABKSRVRQ-WFVLMXAXSA-N

Description

General description

To address challenges of solid formulation manufacturing, we have developed a comprehensive product portfolio to meet with your solid dosage needs in mind. Although solid dose formulations are one of the the most established dosage forms in the pharmaceutical market, the complexity of manufacturing final drug products is becoming more and more challenging. API stability, release kinetics and bioavailability limitations, such as low API solubility, are just a few of many critical obstacles on the way to the market.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Cellulose powder is a commonly used ingredient in food and pharmaceutics. In pharmaceutical applications, cellulose powder has been used primarily for solid oral dosage forms.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable