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EPA 8270/Appendix IX Nitrosamines Mix

certified reference material, 2000 μg/mL each component in methanol

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About This Item

UNSPSC Code:
12000000

grade

certified reference material
TraceCERT®

Quality Level

300

Agency

EPA 8270

product line

TraceCERT®

CofA

current certificate can be downloaded

feature

standard type calibration

packaging

ampule of 1 mL

concentration

2000 μg/mL each component in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

environmental

format

multi-component solution

storage temp.

-10 to -25°C

Related Categories

Application

EPA 8270/Appendix IX nitrosamines mix has been used as a standard solution in the determination of N-nitrosamine in water samples using gas chromatography coupled with mass spectrometry (GC-MS). It has also been used as a standard in the determination of nicotine and N-nitrosamines in indoor house dust using gas chromatography (GC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Analyte

Description
    N-Nitrosodibutylamine
    N-Nitrosodiethylamine
    N-Nitrosodimethylamine
    N-Nitrosodiphenylamine
    N-Nitrosodi-n-propylamine
    N-Nitrosomethylethylamine
    Nitrosomorpholine
    1-Nitrosopiperidine
    1-Nitrosopyrrolidine
    See All (9)

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Flam. Liq. 2 - Skin Sens. 1 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
LRAD5543
LRAD1730
LRAC5636
LRAC0077
LRAB7496

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Determination of nicotine and N-nitrosamines in house dust by pressurized liquid extraction and comprehensive gas chromatography?Nitrogen chemiluminiscence detection
Ramirez N, et al.
Journal of Chromatography A, 1219, 180-187 (2012)
Fully automated determination of N?nitrosamines in environmental waters by headspace solid?phase microextraction followed by GC?MS?MS
Llop A, et al.
Journal of Separation Science, 33, 3692-3700 (2010)
Joy Roasa et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 36(3), 396-404 (2019-02-08)
A method to detect volatile nitrosamines in meat samples was developed using headspace sampling by solid-phase microextraction (HS-SPME), with analysis by GC-MS. A 50/30 µm divinylbenzene/carboxen/polydimethylsiloxane fused silica fibre was selected to extract a total of nine volatile nitrosamines: N-nitrosodimethylamine, N-nitrosomethylethylamine
Wilson Beita-Sandí et al.
Chemosphere, 211, 1091-1097 (2018-09-19)
Cation exchange resins have proved to be efficient in removing precursors of N-nitrosodimethylamine (NDMA). NDMA is a probable human carcinogen with a calculated lifetime cancer risk of 10-6 at 0.7 ng/L in drinking water. This paper investigated the effect of pH and

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