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L9634

Sigma-Aldrich

Laminarin from Laminaria digitata

polysaccharide substrate for laminarinase

Synonym(s):

Laminaran

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

biological source

algae (Laminaria digitata)

Quality Level

form

powder

optical activity

[α]20/D -20 to -5 °, c = 4% (w/v) in water

color

beige

useful pH range

5

solubility

water: 10 mg/mL, clear to slightly hazy, colorless to light yellow

storage temp.

room temp

InChI

1S/C18H32O16/c19-1-4-7(22)10(25)11(26)17(31-4)34-15-9(24)6(3-21)32-18(13(15)28)33-14-8(23)5(2-20)30-16(29)12(14)27/h4-29H,1-3H2/t4-,5-,6-,7-,8-,9-,10+,11-,12-,13-,14+,15+,16?,17?,18?/m1/s1

InChI key

DBTMGCOVALSLOR-VPNXCSTESA-N

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General description

The fronds of Laminaria and Saccharina species contain laminarin, a low molecular weight storage glucan. It is localized to the vacuoles. Laminarin structure contains β-(1,6)-intrachain linked (1,3)-β-d-glucan.

Application

Laminarin from Laminaria digitata has been used:
  • as a stimulant to study its effect on the respiratory burst using haemocytes of P. vannamei
  • as a carbon source to study its effect on enzyme production using Pichia membranifaciens culture
  • as a carbon source for Polaribacter sp. culture

Biochem/physiol Actions

Laminarin is a biologically active compound effective against inflammation. It serves as an antioxidant and anticoagulant. Laminarin also inhibits apoptosis and tumor development. It acts as a predominant source of carbon among aquatic prokaryotes.
Laminarin is a polysaccharide of glucose found in brown algae and utilized as a food reserve.

Other Notes

Polysaccharide; primarily poly(β-Glc-[1→3]) with some β-(1→6) interstrand linkages and branch points.
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Substrates

Substrate for laminarinase.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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N C Moroney et al.
Meat science, 92(4), 423-429 (2012-06-08)
A seaweed extract containing laminarin (L) and fucoidan (F) (L/F) was manufactured from brown seaweed (Laminaria digitata) in spray-dried (L/F-SD) and wet (L/F-WS) forms. The effect of supplementation of pig diets with L/F-SD and L/F-WS (L, 500 mg/kg feed; F
Tomasz Lipinski et al.
Journal of immunology (Baltimore, Md. : 1950), 190(8), 4116-4128 (2013-03-22)
In a previous attempt to generate a protective vaccine against Candida albicans, a β-mannan tetanus toxoid conjugate showed poor immunogenicity in mice. To improve the specific activation toward the fungal pathogen, we aimed to target Dectin-1, a pattern-recognition receptor expressed
Niches of two polysaccharide-degrading Polaribacter isolates from the North Sea during a spring diatom bloom
Xing P, et al.
The ISME Journal, 9(6), 1410-1410 (2015)
Michael H Huesemann et al.
Bioresource technology, 108, 305-309 (2012-01-27)
The objective of this study was to subject mannitol, either as a sole carbon source or in combination with glucose, and aqueous extracts of the kelp Saccharina spp., containing mannitol and laminarin, to acetone-butanol fermentation by Clostridium acetobutylicum (ATCC 824).
Manuel Martinez-Garcia et al.
PloS one, 7(4), e35314-e35314 (2012-04-27)
Microbial hydrolysis of polysaccharides is critical to ecosystem functioning and is of great interest in diverse biotechnological applications, such as biofuel production and bioremediation. Here we demonstrate the use of a new, efficient approach to recover genomes of active polysaccharide

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