Skip to Content
Merck
All Photos(1)

Documents

88315

Sigma-Aldrich

Thesit®

for membrane research

Synonym(s):

Polyethylene glycol dodecyl ether, Polyethylene glycol 400 dodecyl ether, Hydroxypolyethoxydodecane, Lauromacrogol, Macrogol lauryl ether, Polidocanol

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
HO(CH2CH2O)n(CH2)11CH3
CAS Number:
9002-92-0
MDL number:
MFCD00080891
UNSPSC Code:
12352201
PubChem Substance ID:
57653299
NACRES:
NA.21

grade

for membrane research

description

non-ionic

form

solid

mol wt

average mol wt 583

impurities

≤1 ppm peroxides (as H2O2)

CMC

0.1 mM (20-25°C)

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C58H118O24/c1-2-3-4-5-6-7-8-9-10-11-13-60-15-17-62-19-21-64-23-25-66-27-29-68-31-33-70-35-37-72-39-41-74-43-45-76-47-49-78-51-53-80-55-57-82-58-56-81-54-52-79-50-48-77-46-44-75-42-40-73-38-36-71-34-32-69-30-28-67-26-24-65-22-20-63-18-16-61-14-12-59/h59H,2-58H2,1H3

InChI key

IEQAICDLOKRSRL-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Suggested substitute for Lubrol in the preparation of G protein from bovine brain.
Thesit has been used in the reaction buffer to reduce the background sedimentation.

Biochem/physiol Actions

Thesit/Polidocanol possesses in vitro and in vivo anti-angiogenic effects. This sclerosant is mainly used for sclerotherapy.

Legal Information

Thesit is a registered trademark of Desitin Arzneimittel GmbH

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H302,H315,H319,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis and use of biotinylated beta gamma complexes prepared from bovine brain G proteins.
J Dingus et al.
Methods in enzymology, 237, 457-471 (1994-01-01)
K Parsi et al.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 41(2), 267-277 (2010-12-25)
To investigate the in vitro effects of detergent sclerosants sodium tetradecyl sulphate (STS) and polidocanol (POL) on clot formation and lysis. clot kinetics were assessed in whole blood by thromboelastography (TEG®) and rotational thromboelastometry (ROTEM®). Fibrinogen was measured by the
Polidocanol (Lauromacrogol 400) has anti-angiogenic effects in vitro and in vivo
Doganci S, et al.
European Review for Medical and Pharmacological Sciences, 20(7), 1384-1389 (2016)
Measuring protein binding to F-actin by co-sedimentation
Heier JA, et al.
Journal of Visualized Experiments, e55613-e55613 (2017)
G C Valenzuela et al.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 46(5), 593-599 (2013-09-28)
Sclerosant foams are aqueous and break down under the influence of gravity, pressure, and temperature. The aim of this study was to investigate the effects of temperature on foam stability. Sodium tetradecyl sulphate (STS) and polidocanol (POL) liquid and foam
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service