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271748

Sigma-Aldrich

Pyridoxal hydrochloride

99%

Synonym(s):

3-Hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde hydrochloride, PL HCl

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About This Item

Empirical Formula (Hill Notation):
C8H9NO3 · HCl
CAS Number:
Molecular Weight:
203.62
Beilstein:
3656994
EC Number:
MDL number:
UNSPSC Code:
12352205
PubChem Substance ID:
NACRES:
NA.79

biological source

synthetic (Organic)

Quality Level

Assay

99%

form

powder

color

white to off-white

mp

173 °C (dec.) (lit.)

storage temp.

2-8°C

SMILES string

Cl[H].[H]C(=O)c1c(CO)cnc(C)c1O

InChI

1S/C8H9NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,4,10,12H,3H2,1H3;1H

InChI key

FCHXJFJNDJXENQ-UHFFFAOYSA-N

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General description

Pyridoxal, a form of vitamin B6, is a water soluble vitamin. The food sources of vitamin B6 include grains, nuts, fruits, vegetables and meat.

Application

Pyridoxal hydrochloride has been used to test its potential contribution to plant stress tolerance. It has also been used as a supplement in modified M9 minimal medium to culture E. coli BL21(DE3) cells for expression of 15N-labeled ATG101.
For the labeling of amino acids and their detection in picomolar amounts; Coenzymes and Cofactors, vol. 1: Vitamin B6, Pyridoxal Phosphate

Biochem/physiol Actions

Vitamin B6 plays a key role in metabolism of both carbohydrates and amino acids. It is implicated in the synthesis of neurotransmitters like dopamine from L-DOPA, serotonin from 5-HTP, and γaminobutyric acid (GABA) from glutamate. Vitamin B6 plays a major role in maintenance of a healthy nervous system.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin
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CNS Neuroscience & Therapeutics (2019)
Root metabolic plasticity underlies functional diversity in mycorrhiza-enhanced stress tolerance in tomato
Rivero J, et al.
The New phytologist, 220(4), 1322-1336 (2018)
Vitamin B6 and its role in cell metabolism and physiology
Parra M, et al.
Cells, 7(7), 84-84 (2018)

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