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D2954600

Docosahexaenoic acid ethyl ester

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

4,7,10,13,16,19-Docosahexaenoic acid ethyl ester

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About This Item

Empirical Formula (Hill Notation):
C24H36O2
CAS Number:
Molecular Weight:
356.54
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

docosahexaenoic acid ethyl ester

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

InChI

1S/C24H36O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26-4-2/h5-6,8-9,11-12,14-15,17-18,20-21H,3-4,7,10,13,16,19,22-23H2,1-2H3/b6-5+,9-8+,12-11+,15-14+,18-17+,21-20+

InChI key

ITNKVODZACVXDS-YATCGRJWSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Docosahexaenoic acid ethyl ester EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Toshinori Hoshi et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(12), 4816-4821 (2013-03-15)
Long-chain polyunsaturated omega-3 fatty acids such as docosahexaenoic acid (DHA), found abundantly in oily fish, may have diverse health-promoting effects, potentially protecting the immune, nervous, and cardiovascular systems. However, the mechanisms underlying the purported health-promoting effects of DHA remain largely
P Green et al.
Biochimica et biophysica acta, 1531(1-2), 156-164 (2001-03-30)
Previously we have shown that intraamniotic administration of ethyl docosahexaenoate (Et-DHA) to pregnant rats resulted in decreased lipid peroxidation in the fetal brain, under a variety of conditions (S. Glozman, P. Green, E. Yavin, J. Neurochem. 70 (1998) 2482-2491). In
Alfonso Valenzuela et al.
Annals of nutrition & metabolism, 49(1), 49-53 (2005-03-01)
Docosahexaenoic acid (C22:6, DHA) is an omega-3 fatty acid required for the normal development of the mammalian nervous and visual system. DHA is provided by the mother during pregnancy and lactating period. Mother's DHA supplementation during pregnancy, and even before
M Teresa Noguer et al.
Investigative ophthalmology & visual science, 51(4), 2277-2285 (2009-11-26)
Purpose. To assess the possible beneficial effects of docosahexaenoic acid (DHA) ethyl ester on visual function in DHA-deficient patients with peroxisome biogenesis disorders (PBDs). Methods. A total of 23 patients were studied, of whom 2 had classic Zellweger syndrome and
K Umegaki et al.
Free radical research, 34(4), 427-435 (2001-05-01)
We compared the influence of docosahexaenoic acid (DHA) supplementation on oxidative DNA damage in bone marrow between young and aged rats. As a marker of oxidative DNA damage, 8-hydroxydeoxyguanosine (8-OHdG) in DNA was analyzed. Young (5-week-old) and aged (100-week-old) female

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