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Key Documents

D-019

Supelco

Dihydrocodeine hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C18H23NO3·HCl
CAS Number:
Molecular Weight:
337.84
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

2-8°C

SMILES string

Cl.COc1ccc2C[C@@H]3[C@@H]4CC[C@H](O)[C@@H]5Oc1c2[C@]45CCN3C

InChI

1S/C18H23NO3.ClH/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19;/h3,6,11-13,17,20H,4-5,7-9H2,1-2H3;1H/t11-,12+,13-,17-,18-;/m0./s1

InChI key

VMZXMTVGOAQUEN-FFHNEAJVSA-N

General description

A Certified Snap-N-Spike® Solution suited for use as starting material in calibrators and controls for a variety of LC/MS or GC/MS applications from urine drug testing and pain prescription monitoring to forensic analysis and pharmaceutical research. Dihydrocodeine is an opioid analgesic developed for treatment of moderate to severe pain and as an antitussive.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Cautious advice.
Lieselotte Windhövel
Deutsches Arzteblatt international, 106(4), 57-57 (2009-07-01)
Erythema multiforme major putatively induced by dihydrocodeine phosphate.
Y Matsuzawa et al.
Clinical and experimental dermatology, 35(6), 673-674 (2010-03-30)
Wojciech Leppert et al.
Current pharmaceutical biotechnology, 12(2), 306-312 (2010-11-06)
To assess tramadol and O-desmethyltramadol (M1) concentrations and their correlations with analgesia in patients with cancer pain. Thirty opioid-naive patients with nociceptive pain intensity on VAS (visual analogue scale) > 40 received controlled-release tramadol as the first (15 patients, 7
[Q & A. A patient brought in a comatose state, displaying acute hepatic disorder and an area of high absorption in the stomach in CT images].
Motohiko Tanaka et al.
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 108(4), 665-666 (2011-06-24)
Wojciech Leppert
Current drug metabolism, 11(6), 494-506 (2010-06-15)
Dihydrocodeine (DHC) is a semi-synthetic analogue of codeine which was formed by the hydrogenation of the double tie in the main chain of the codeine molecule. DHC is used as an analgesic, antitussive and antidiarrhoeal agent; it is also used

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