880138P

DSPE-PEG(2000) Carboxy NHS

Avanti Research^™ - A Croda Brand

• Synonym(s): DSPE-PEG(2000) Carboxy NHS, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000, NHS ester] (sodium salt)
• Empirical Formula (Hill Notation): C₁₃₅H₂₆₀N₂NaO₅₇P
• CAS Number: 2410279-87-5
• Molecular Weight: 2877.45
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: package of 1 × 10 mg
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• application(s): advanced drug delivery
• lipid type: polymerizable lipids
• shipped in: dry ice
• storage temp.: −20°C

Description

Application

• Enhanced detection of myeloma cells: DSPE-PEG(2000) Carboxy was used to create fluorescence labeled XT5 modified nano-capsules, enhancing the sensitivity of detecting myeloma cells. This application demonstrates its potential in biomedical diagnostics and targeted therapy (Norouz Dizaji et al., 2022).


• Improving drug encapsulation efficiency: The use of DSPE-PEG(2000) Carboxy in pre-formed liposomes for drug delivery showcases a method that significantly improves carboplatin encapsulation, highlighting its role in optimizing chemotherapeutic drug formulations (Wehbe et al., 2017).


• Targeted drug delivery for cardiovascular diseases: DSPE-PEG(2000) Carboxy was integral in the development of PEGylated-nanoliposomal formulations of clusterin, aimed at treating amyloidogenic light chain-induced endothelial dysfunction, underscoring its utility in targeted cardiovascular therapies (Guzman-Villanueva et al., 2018).

Packaging

5 mL Amber Glass Screw Cap Vial (880138P-25MG)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable