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810240P

Avanti

TopFluor TMR PA

Avanti Research - A Croda Brand 810240P, powder

Synonym(s):

1-oleoyl-2-(6-((4,4-difluoro-1,3-dimethyl-5-(4-methoxyphenyl)-4-bora-3α,4α-diaza-s-indacene-2-propionyl)amino)hexanoyl)-sn-glycero-3- phosphate (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C48H74 BF2N4 O10P
CAS Number:
Molecular Weight:
946.90
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810240P-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 810240P

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidic acid (PA) is a diacyl-glycerophospholipid that consists of a glycerol and an alcohol moiety, having two fatty acids and a phosphate group esterified at positions 1, 2, and 3, respectively.

Biochem/physiol Actions

Phosphatidic acid (PA) is a signaling molecule that is synthesized in the endoplasmic reticulum (ER). It is transported to the mitochondrial outer membrane to stimulate mitofusin (Mfn)-mediated fusion. PA is a major intermediate metabolite involved in the synthesis of membrane glycerophospholipids, which include phosphatidylcholine (PC), phosphatidylserine (PS), phosphatidylethanolamine (PE), and phosphatidylserine (PS).

Packaging

5 mL Amber Glass Screw Cap Vial (810240P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Phosphatidic acid and cardiolipin coordinate mitochondrial dynamics
Brain Lipids in Synaptic Function and Neurological Disease: Clues to Innovative Therapeutic Strategies for Brain Disorders, 28(1), 67-76 (2015)
Phosphatidic acid and cardiolipin coordinate mitochondrial dynamics
Multifunctional Systems for Combined Delivery Biosensing and Diagnostics, 28(1), 67-76 (2020)
Shoichiro Kameoka et al.
Trends in cell biology, 28(1), 67-76 (2017-09-16)
Membrane organelles comprise both proteins and lipids. Remodeling of these membrane structures is controlled by interactions between specific proteins and lipids. Mitochondrial structure and function depend on regulated fusion and the division of both the outer and inner membranes. Here

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