H1384

Hypotaurine

≥98% (TLC)

• Synonym(s): 2-Aminoethanesulfinic acid
• Empirical Formula (Hill Notation): C₂H₇NO₂S
• CAS Number: 300-84-5
• Molecular Weight: 109.15
• MDL number: MFCD00038197
• UNSPSC Code: 12352100
• PubChem Substance ID: 57654233
• NACRES: NA.22

Properties

• Assay: ≥98% (TLC)
• color: white to off-white
• solubility: H₂O: 100 mg/mL
• SMILES string: NCCS(O)=O
• InChI: 1S/C2H7NO2S/c3-1-2-6(4)5/h1-3H2,(H,4,5)
• InChI key: VVIUBCNYACGLLV-UHFFFAOYSA-N

Description

Application

Hypotaurine has been used as a supplement in fertilization medium (Fert- tyrode albumin lactate pyruvate (TALP)), which used in in-vitro fertilization and evaluation of embryo development. It is also used as a H₂S scavenger.

Biochem/physiol Actions

Hypotaurine, a cystamine analog, is the precursor for taurine synthesis. It can act as an antioxidant and singlet oxygen scavenger, thereby protecting cells from oxidative damage. Hypotaurine is reported to play an important role in the maintenance and stimulation of sperm motility and also in vitro fertilization and embryo development.

Antioxidant that binds hydroxyl radicals. Endogenous inhibitory neuromodulator that is blocked by strychnine and picrotoxin. Inhibits the Na²⁺-dependent transport of GABA and β-alanine. It is a degradation product of cysteine and a precursor of taurine.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves