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Key Documents

A8509

Sigma-Aldrich

Lithium acetoacetate

≥90% (HPLC)

Synonym(s):

Acetoacetic acid lithium salt

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About This Item

Linear Formula:
CH3COCH2COOLi
CAS Number:
Molecular Weight:
108.02
Beilstein:
5774841
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level

Assay

≥90% (HPLC)

form

powder

storage temp.

−20°C

SMILES string

[Li+].CC(=O)CC([O-])=O

InChI

1S/C4H6O3.Li/c1-3(5)2-4(6)7;/h2H2,1H3,(H,6,7);/q;+1/p-1

InChI key

UTLRZTUJSMCBHB-UHFFFAOYSA-M

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Application

Lithium acetoacetate can be used as an acetoacetate standard for the measurement of acetoacetate in biological samples.[1][2] It can also be used for the preparation of sodium acetoacetate.[3]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Development of a butanologenic strain with high selectivity for butanol production is often proposed as a possible route for improving the economics of biobutanol production by solventogenic Clostridium species. The acetoacetate decarboxylase (aadc) gene encoding acetoacetate decarboxylase (AADC), which catalyzes
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Acetoacetate (AA) and 2-methylacetoacetate (MAA) are accumulated in metabolic disorders such as diabetes and isoleucinemia. Here we examine the mechanism of AA and MAA aerobic oxidation initiated by myoglobin (Mb)/H(2)O(2). We propose a chemiluminescent route involving a dioxetanone intermediate whose
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Crystal structures of divalent metal-dependent pyruvate aldolase, HpaI, in complex with substrate and cleavage products were determined to 1.8-2.0 Å resolution. The enzyme·substrate complex with 4-hydroxy-2-ketoheptane-1,7-dioate indicates that water molecule W2 bound to the divalent metal ion initiates C3-C4 bond

Questions

  1. Whats the concentration or gram of Lithium in the A8509 lithium acetoacetate salt?

    1 answer
    1. If the product were 100% pure, lithium would comprise 6.4% (6.941 g/mol / 108.02 g/mol). For every gram of product, ~64 milligrams would be lithium by mass. This value would need to be multiplied by the lot-specific product purity in order to obtain a more accurate value.

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