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Sigma-Aldrich

TentaGel™ S RAM

TentaGel™ S RAM

extent of labeling: ~0.24 mmol/g loading

Synonym(s):

N-Fmoc-4′-[poly(oxyethylene)carbamoylmethoxy]-2,4-dimethoxybenzhydrylamine polymer-bound, Poly(oxyethylene)-RAM polymer-bound

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About This Item

UNSPSC Code:
12352116
PubChem Substance ID:
24888643
NACRES:
NA.22
Pricing and availability is not currently available.

product line

TentaGel™

Quality Level

100

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

extent of labeling

~0.24 mmol/g loading

particle size

~90 μm

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

Related Categories

General description

TentaGel™ S RAM is a Fmoc protected resin and modified with a Rink amide linker, suitable for solid-phase peptide synthesis.

Application

TentaGel™ S RAM is used in the solid-phase synthesis of aryl ethers by Mitsunobu reaction. Additionally, it can be used in Suzuki-coupling reaction of organoboronic acids with iodo- and bromo-substituted benzoic acid.[1][2]

Legal Information

TentaGel is a trademark of Rapp Polymere GmbH

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM8657
BCCM4147
BCCL7712
BCCJ4538
BCCG1013

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Rapid microwave-assisted Suzuki coupling on solid-phase
Tetrahedron Letters, 37, 8219-8222 (1996)
Solid phase synthesis of aryl ethers via the Mitsunobu reaction
Tetrahedron Letters, 36, 3789-3792 (1995)
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  1. Plano, TX
    • Review 1
    • Vote 1
    2 out of 5 stars.

    Good resin, but poor job on description

    The resin comes Fmoc protected, a fact which only becomes apparent when you check the synonym. I wasted nearly a bottle of this resin on a synthesis, before I became aware of the fact that it is protected.

    Helpful?

    1. Response from MilliporeSigma:

      Thank you for taking the time to leave a review and suggesting product information improvements! We appreciate this feedback. We are also sorry to hear that your experience did not meet expectations. We would like to learn more about your application to see if there is anything we can do to help troubleshoot this issue or suggest a different resin. When you have a moment, please contact us by visiting https://www.sigmaaldrich.com/support/customer-support and submit a Report Product Issue ticket. We look forward to hearing from you soon!

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