128635

2-Hydroxyethyl methacrylate

contains ≤250 ppm monomethyl ether hydroquinone as inhibitor, 97%

• Synonym(s): 1,2-Ethanediol mono(2-methylpropenoate), Glycol methacrylate, HEMA
• Linear Formula: CH₂=C(CH₃)COOCH₂CH₂OH
• CAS Number: 868-77-9
• Molecular Weight: 130.14
• Beilstein: 1071583
• EC Number: 212-782-2
• MDL number: MFCD00002863
• UNSPSC Code: 12162002
• PubChem Substance ID: 24847870
• NACRES: NA.23

Properties

• vapor density: 5 (vs air)
• vapor pressure: 0.01 mmHg ( 25 °C)
• Assay: 97%
• form: liquid
• contains: ≤250 ppm monomethyl ether hydroquinone as inhibitor
• refractive index: n20/D 1.453 (lit.)
• bp: 67 °C/3.5 mmHg (lit.)
• density: 1.073 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: CC(=C)C(=O)OCCO
• InChI: 1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3
• InChI key: WOBHKFSMXKNTIM-UHFFFAOYSA-N

Description

General description

2-Hydroxyethyl methacrylate (HEMA) was the first monomer to be used to synthesize hydrogels for biomedical applications.The water swelling properties of HEMA are enhanced by copolymerization with more hydrophilic monomers.HEMA finds wide applications for drug delivery.

Application

HEMA is used in the synthesis of biologically functional poly (2-hydroxyethyl methacrylate) (PHEMA) coplymers. It is also used to prepare light responsive membranes of PHEMA, HEMA/ acrylamide based specific drug release hydrogel, and water soluble HEMA/methacrylic acid hydrogel for drug delivery. Effects of HEMA on the migration of dental pulp stem cells (in vitro) may be studied.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H317,H319
• Precautionary Statements: P261 - P264 - P272 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 222.8 °F - closed cup
• Flash Point(C): 106 °C - closed cup