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F1177

Sigma-Aldrich

Fluorescein hyaluronic acid

>95%, powder

Synonym(s):

Hyaluronic Acid Fluorescein Conjugate

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About This Item

MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25

Quality Level

Assay

>95%

form

powder

mol wt

~800,000 Da

color

orange

solubility

H2O: soluble 1 mg/mL

storage temp.

2-8°C

Application

Fluorescein hyaluronic acid has been used in the fluorescence imaging of hyaluronic acid (HA) and dextran surface coated filmsand patterned surfaces. It has also been used in confocal fluorescence microscopy to localize hyaluronic acid in collagen/HA composite gels .

Biochem/physiol Actions

Hyaluronan macromolecules (HAs) coupled to fluorescein amine is exploited to screen the hyaluronidase activity using fluorescence correlation spectroscopy (FCS) by measuring the quenching of fluorescein-labeled HA fragments. It binds on cell surface of malignant mesothelioma derived from human tumors.
Used to bind on cell surface of malignant mesothelioma derived from human tumors.

Other Notes

From cock′s comb or by fermentation.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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