C5020

Cefazolin sodium salt

89.1-110.1%

• Synonym(s): Cefazoline sodium, Monosodium cefazolin
• Empirical Formula (Hill Notation): C₁₄H₁₃N₈NaO₄S₃
• CAS Number: 27164-46-1
• Molecular Weight: 476.49
• Beilstein: 3585038
• EC Number: 248-278-4
• MDL number: MFCD00056883
• UNSPSC Code: 51282532
• PubChem Substance ID: 24278318
• NACRES: NA.76

Properties

• Assay: 89.1-110.1%
• form: powder
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria
• Mode of action: cell wall synthesis | interferes
• storage temp.: 2-8°C
• SMILES string: [Na+].Cc1nnc(SCC2=C(N3[C@H](SC2)[C@H](NC(=O)Cn4cnnn4)C3=O)C([O-])=O)s1
• InChI: 1S/C14H14N8O4S3.Na/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21;/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26);/q;+1/p-1/t9-,12-;/m1./s1
• InChI key: FLKYBGKDCCEQQM-WYUVZMMLSA-M

Description

General description

Chemical structure: ß-lactam

Biochem/physiol Actions

Used to study the effect of expression, binding and inhibition of penicillin-binding proteins, especially PBP2 and PBP4 on bacterial cell wall mucopeptide synthesis.

Preparation Note

Freely soluble in water, very slightly soluble in chloroform and ethanol.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H317,H334
• Precautionary Statements: P261 - P280 - P342 + P311
• Hazard Classifications: Resp. Sens. 1 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves