218805

Caspase-9 Substrate II, Colorimetric

The Caspase-9 Substrate II, Colorimetric serves as the substrate for Caspase-9.

• Synonym(s): Caspase-9 Substrate II, Colorimetric, Ac-LEHD- pNA, Ac-LEHD-pNA
• Empirical Formula (Hill Notation): C₂₉H₃₈N₈O₁₁
• Molecular Weight: 674.66
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: lyophilized
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated; protect from light
• solubility: DMSO: 5 mg/mL
• shipped in: ambient
• storage temp.: −20°C

Description

General description

A colorimetric substrate for caspase-9. Cleavage is monitored colorimetrically at ~405 nm.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Caspase-9

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Standard Handling (A)

Sequence

Ac-Leu-Glu-His-Asp-pNA

Other Notes

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable