T22403
Tetrahydrothiophene 1-oxide
96%
Synonym(s):
Tetramethylene sulfoxide
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About This Item
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Quality Level
Assay
96%
refractive index
n20/D 1.52 (lit.)
bp
235-237 °C (lit.)
density
1.158 g/mL at 25 °C (lit.)
SMILES string
O=S1CCCC1
InChI
1S/C4H8OS/c5-6-3-1-2-4-6/h1-4H2
InChI key
ISXOBTBCNRIIQO-UHFFFAOYSA-N
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Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
233.6 °F - closed cup
Flash Point(C)
112 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Journal of medicinal chemistry, 26(6), 916-922 (1983-06-01)
Sulfoxides and amides were tested as inhibitors of liver alcohol dehydrogenase and ethanol metabolism in rats. With both series of compounds, increasing the hydrophobicity resulted in better inhibition, and introduction of polar groups reduced inhibition. Of the cyclic sulfoxides, tetramethylene
Journal of bacteriology, 169(6), 2862-2865 (1987-06-01)
Escherichia coli used tetrahydrothiophene 1-oxide (THTO) as an electron acceptor for anaerobic growth with glycerol as a carbon source; the THTO was reduced to tetrahydrothiophene. Cell extracts also reduced THTO to tetrahydrothiophene in the presence of a variety of electron
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Kinetics and products of peroxynitrite anion O=NOO- reactions, catalyzed by water-soluble manganese and iron porphyrins, were studied under basic and neutral conditions. In the absence of organic substrates peroxynitrite decomposes catalytically to give nitrite and dioxygen as major products. Catalytic
The Biochemical journal, 278 ( Pt 3), 659-665 (1991-09-15)
We used titration with the inhibitors tetramethylene sulphoxide and isobutyramide to assess quantitatively the importance of alcohol dehydrogenase in regulation of ethanol oxidation in rat hepatocytes. In hepatocytes isolated from starved rats the apparent Flux Control Coefficient (calculated assuming a
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