A76109
3-Amino-1-propanesulfonic acid
97%
Synonym(s):
3APS, Homotaurine, Tramiprosate
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All Photos(2)
About This Item
Linear Formula:
H2N(CH2)3SO3H
CAS Number:
Molecular Weight:
139.17
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
97%
form
solid
mp
293 °C (dec.) (lit.)
SMILES string
NCCCS(O)(=O)=O
InChI
1S/C3H9NO3S/c4-2-1-3-8(5,6)7/h1-4H2,(H,5,6,7)
InChI key
SNKZJIOFVMKAOJ-UHFFFAOYSA-N
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Application
Important gabamimetic agent-evokes neurological responses similar to those elicited by γ-aminobutyric acid (GABA).
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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A comparison of the effects of GABA, 3-aminopropanesulphonic acid and imidazoleacetic acid on the frog spinal cord.
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Neuropharmacology, 17(1), 13-19 (1978-01-01)
Riv. Farmacol. Ter., 7, 155-155 (1976)
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Amyloid beta-peptide (Abeta) is a major constituent of senile plaques in Alzheimer's disease (AD). Neurotoxicity results from the conformational transition of Abeta from random-coil to beta-sheet and its oligomerization. Among a series of ionic compounds able to interact with soluble
P S Aisen et al.
Neurology, 67(10), 1757-1763 (2006-11-04)
As a potential disease-modifying treatment for Alzheimer disease (AD), 3-amino-1-propanesulfonic acid (3APS) is a compound that binds to amyloid beta (Abeta), a toxic protein known to aggregate, leading to amyloid plaque deposition in the brain. We assessed the safety, tolerability
Chem. Abstr., 86, 25685r-25685r (1977)
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