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Documentos

1719000

USP

Warfarina

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin, Coumafene

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About This Item

Fórmula empírica (notación de Hill):
C19H16O4
Número de CAS:
81-81-2
Peso molecular:
308.33
Beilstein/REAXYS Number:
8868198
MDL number:
MFCD00006854
UNSPSC Code:
41116107
PubChem Substance ID:
329751510
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

warfarin

manufacturer/tradename

USP

mp

162-164 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(=O)CC(c1ccccc1)C2=C(O)c3ccccc3OC2=O

InChI

1S/C19H16O4/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22/h2-10,15,21H,11H2,1H3

InChI key

PJVWKTKQMONHTI-UHFFFAOYSA-N

Gene Information

human ... VKORC1(79001)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Warfarin USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Warfarin Sodium
  • Warfarin Sodium Tablets
  • Warfarin Sodium for Injection

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Legal Information

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Repr. 1A - STOT RE 1 Oral

target_organs

Blood

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Phenprocoumon ≥97% (HPLC)

Sigma-Aldrich

SML2365

Phenprocoumon

Timerosal United States Pharmacopeia (USP) Reference Standard

USP

1659000

Timerosal

Brodifacoum PESTANAL®, analytical standard

Supelco

46036

Brodifacoum

Urea United States Pharmacopeia (USP) Reference Standard

USP

1706698

Urea

Ibuprofen ≥98% (GC)

Sigma-Aldrich

I4883

Ibuprofen

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Temporary interruption of oral anticoagulation for procedures is often required, and some propose using bridging anticoagulation. However, the use and outcomes of bridging during oral anticoagulation interruptions in clinical practice are unknown. The Outcomes Registry for Better Informed Treatment of
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Pathologic blood clotting is a leading cause of morbidity and mortality in the developed world, underlying deep vein thrombosis, myocardial infarction, and stroke. Genetic predisposition to thrombosis is still poorly understood, and we hypothesize that there are many additional risk
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This study aimed to evaluate the cost-effectiveness of dabigatran and rivaroxaban compared with warfarin for the prevention of stroke in patients with atrial fibrillation (AF) in Singapore. A Markov model was constructed to compare the lifetime costs, quality-adjusted life-years (QALYs)
ACP Journal Club: mechanical left atrial appendage closure was noninferior and superior to warfarin in atrial fibrillation.
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Annals of internal medicine, 162(8), JC4-JC4 (2015-04-22)
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