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Merck

1602502

USP

Retinyl palmitate

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

Vitamin A palmitate, all−trans−Retinol palmitate

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About This Item

Fórmula empírica (notación de Hill):
C36H60O2
Número de CAS:
Peso molecular:
524.86
Beilstein/REAXYS Number:
1917366
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

retinyl compounds

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(CCCCCCCCCCCCCCC)=O)C(C)(C)CCC1

InChI

1S/C36H60O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-25-35(37)38-30-28-32(3)23-20-22-31(2)26-27-34-33(4)24-21-29-36(34,5)6/h20,22-23,26-28H,7-19,21,24-25,29-30H2,1-6H3/b23-20+,27-26+,31-22+,32-28+

InChI key

VYGQUTWHTHXGQB-FFHKNEKCSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Application


  • Retinyl palmitate in nanoemulgels for skin diseases: Research explores the application of retinyl palmitate in innovative nanoemulgels, demonstrating its efficacy in treating skin conditions through enhanced delivery mechanisms. This aligns with its use in skin rejuvenation and anti-aging treatments, providing a novel approach for topical therapy (Sghier et al., 2024).

  • Stability and efficacy in UVB-induced skin photoaging: A study assessed retinyl palmitate′s efficacy against UVB-induced photoaging, showing significant protective effects on the skin. This underscores its potential as a high-purity biochemical assay component for studying retinoid signaling and its impact on skin health (Shu et al., 2023).

  • Enhanced anti-photoaging therapy: Comparative research among various retinoids, including retinyl palmitate, highlights its superior anti-inflammatory and antioxidative activities, positioning it as a preferred choice for anti-photoaging treatments. The study emphasizes its application in biochemical assays and as a vitamin A source in tissue engineering (Shu et al., 2023).

Biochem/physiol Actions

Review: Vitamin A metabolism.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Health hazard

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 2

flash_point_f

381.2 °F

flash_point_c

194.00 °C


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Vitamin A
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 44(2), 4632-4632 (2019)
Vitamin A Assay
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 38(6), 6801-6801 (2014)
Shaikh Meshbahuddin Ahmad et al.
Contemporary clinical trials, 39(2), 269-279 (2014-10-02)
In recent years, neonatal vitamin A supplementation is considered as an essential infant-survival intervention but the evidence is not conclusive. This randomized controlled clinical trial was conducted to evaluate the effect of vitamin A on immune competence in early infancy.
Hans L Mooij et al.
Journal of lipid research, 56(3), 665-673 (2015-01-09)
Elevated nonfasting TG-rich lipoprotein levels are a risk factor for CVD. To further evaluate the relevance of LDL-receptor (LDLr) pathway and heparan sulfate proteoglycans (HSPGs) in TG homeostasis, we analyzed fasting and postprandial TG levels in mice bearing combined heterozygous
Xiaofeng Liao et al.
PloS one, 10(3), e0118176-e0118176 (2015-03-17)
Roles of all-trans-retinoic acid (tRA), a metabolite of vitamin A (VA), in both tolerogenic and immunogenic responses are documented. However, how tRA affects the development of systemic autoimmunity is poorly understood. Here we demonstrate that tRA have paradoxical effects on

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