1481306

Oxaliplatin System Suitability

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: [SP-4-2-(1R-trans)]-Dichloro(1,2-cyclohexanediamine-N,N′)platinum, [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N′)dichloridoplatinum(II)
• Fórmula empírica (notación de Hill): C₆H₁₄Cl₂N₂Pt
• Número de CAS: 61848-66-6
• Peso molecular: 380.17
• UNSPSC Code: 41116107
• NACRES: NA.24

Propiedades

• grade: pharmaceutical primary standard
• API family: oxaliplatin
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• InChI: 1S/C6H12N2.2ClH.Pt/c7-5-3-1-2-4-6(5)8;;;/h5-8H,1-4H2;2*1H;/q-2;;;+4/p-2
• InChI key: UUERTZXRKZEANK-UHFFFAOYSA-L

Descripción

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

• Innovative Lung Drug Delivery: Oxaliplatin system suitability is crucial in the development of inhalable porous particles for efficient lung drug delivery systems. This application significantly improves therapeutic outcomes in diseases such as tuberculosis by ensuring optimal particle size and drug formulation consistency for deep lung penetration (Campos Pacheco et al., 2024).


• Pulmonary Health Monitoring: Respirable cristobalite exposure effects are critically assessed in workplace settings using oxaliplatin as a reference standard in silica-induced pulmonary inflammation studies. This research is vital for occupational health safety, enhancing our understanding of chronic respiratory conditions caused by inhalable mineral particles (Heine et al., 2024).


• Respiratory Disease Research: Oxaliplatin system suitability standards are employed in environmental health studies to evaluate the impact of respirable dust on lung health. Such standards ensure the accuracy and reliability of data crucial for developing interventions aimed at reducing the incidence of respiratory diseases in industrial settings (Beard et al., 2024).


• Environmental Safety Analysis: High-purity oxaliplatin is used in analytical methods to differentiate asbestos from cristobalite, aiding in environmental safety assessments and regulatory compliance. This application ensures the protection of public health by identifying hazardous materials in building and construction environments (Lee et al., 2024).


• Occupational Health Standard Development: Oxaliplatin standards are integral in comparative studies of occupational exposure limits internationally, particularly concerning coal dust which includes respirable cristobalite. Such research informs policy-making and helps establish safer working conditions across different industries (Li and Zhu, 2024).

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Información de seguridad

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H319,H340,H351,H360D,H372
• pcodes: P202 - P260 - P264 - P280 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Carc. 2 - Eye Irrit. 2 - Muta. 1B - Repr. 1B - STOT RE 1
• target_organs: Nervous system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable