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1466641

USP

N-Nitrosodibutylamine (NDBA)

Name: <I>N</I>-Nitrosodibutylamine (NDBA)
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

N-Butyl-N-nitroso-1-butanamine

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Fórmula empírica (notación de Hill):

C₈H₁₈N₂O

Número CAS:

924-16-3

Peso molecular:

158.24

MDL number:

MFCD00013892

UNSPSC Code:

41116107

NACRES:

NA.24

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Propiedades

grade

pharmaceutical primary standard

agency

USP

packaging

pkg of 1 mg

manufacturer/tradename

USP

application(s)

pharmaceutical
pharmaceutical (small molecules)
pharmaceutical

format

neat

storage temp.

−20°C

SMILES string

N(N=O)(CCCC)CCCC

InChI

1S/C8H18N2O/c1-3-5-7-10(9-11)8-6-4-2/h3-8H2,1-2H3

InChI key

YGJHZCLPZAZIHH-UHFFFAOYSA-N

Descripción

General description

Find answers to frequently asked questions on USP products in USP FAQs.

Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.

This product is provided as delivered and specified by the issuing Pharmacopoeia. For further information and support, including certificate/ product information sheets, please go to the website of the issuing Pharmacopoeia.

Application

N-Nitrosodibutylamine (NDBA) USP reference standard is intended for use only as specifically prescribed in the United States Pharmacopoeia.

It is also used to prepare standard, nitrosamine standards stock solution mixture, and sensitivity solutions to determine NDBA impurity in drug substances and drug products (valsartan, irbesartan, and losartan potassium etc.) by chromatography according to general chapter <1469> of United States Pharmacopeia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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Este artículo	PHR3608	442685	1466674
USP 1466641 N-Nitrosodibutylamine (NDBA)	Supelco PHR3608 N-Nitrosodibutylamine (NDBA)	Supelco 442685 N-Nitrosodi-n-butylamine	USP 1466674 N-Nitrosodimethylamine (NDMA)
description United States Pharmacopeia (USP) Reference Standard	description certified reference material, pharmaceutical secondary standard	description analytical standard	description United States Pharmacopeia (USP) Reference Standard
application(s) pharmaceutical (small molecules)	application(s) pharmaceutical	application(s) environmental	application(s) USP Biologics pharmaceutical (small molecules)
format neat	format -	format neat	format single component solution (solution in methanol)
grade pharmaceutical primary standard	grade certified reference material, pharmaceutical secondary standard	grade analytical standard	grade pharmaceutical primary standard
storage temp. −20°C	storage temp. -	storage temp. 2-30°C	storage temp. −20°C
packaging pkg of 1 mg	packaging pkg of 1 mL	packaging ampule of 100 mg	packaging pkg of 1 mg
manufacturer/tradename USP	manufacturer/tradename -	manufacturer/tradename Manufactured by: Sigma-Aldrich Production GmbH, Switzerland	manufacturer/tradename USP

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Pictogramas

GHS02,GHS06,GHS08

Palabra de advertencia

Danger

Códigos de peligro

H225,H301 + H311 + H331,H370

Indicaciones de precaución

P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos diana

Eyes,Central nervous system

Clase de almacenamiento

3 - Flammable liquids

¿Qué está pasando?

WGK 2

Punto de inflamación (°F)

49.5 °F

Punto de inflamación (°C)

9.7 °C

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Certificados de análisis (COA)

Lot/Batch Number

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