1463960

Nitazoxanide

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: NTZ; 2-(Acetyloxy)-N-(5-nitro-2-thiazolyl)benzamide
• Fórmula empírica (notación de Hill): C₁₂H₉N₃O₅S
• Número CAS: 55981-09-4
• Peso molecular: 307.28
• NACRES: NA.24
• PubChem Substance ID: 329750564
• UNSPSC Code: 41116107
• MDL number: MFCD00416599

Propiedades

• grade: pharmaceutical primary standard
• agency: USP
• API family: nitazoxanide
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: CC(=O)Oc1ccccc1C(=O)Nc2ncc(s2)[N+]([O-])=O
• InChI: 1S/C12H9N3O5S/c1-7(16)20-9-5-3-2-4-8(9)11(17)14-12-13-6-10(21-12)15(18)19/h2-6H,1H3,(H,13,14,17)
• InChI key: YQNQNVDNTFHQSW-UHFFFAOYSA-N

Descripción

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Nitazoxanide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

Nitazoxanide is an inhibitor of pyruvate-ferredoxin oxidoreductase (PFOR); Antimicrobial recently found to kill both non-replicating and replicating mycobacteria.

Nitazoxanide is an inhibitor of pyruvate-ferredoxin oxidoreductase (PFOR); FDA approved anti-parasitic drug (2002). Recent work (C & EN Sept. 14, 2009, p. 28) highlights that NTZ kills non-replicating and replicating TB bacteria and no apparent resistance is detected.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable