1292303

Glimepiride

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: Glimepiride
• Fórmula empírica (notación de Hill): C₂₄H₃₄N₄O₅S
• Número de CAS: 93479-97-1
• Peso molecular: 490.62
• Número MDL: MFCD00878417
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329749940
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: glimepiride
• fabricante / nombre comercial: USP
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• cadena SMILES: CCC1=C(C)CN(C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)N[C@H]3CC[C@H](C)CC3)C1=O
• InChI: 1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)/t16-,19-
• Clave InChI: WIGIZIANZCJQQY-RUCARUNLSA-N
• Información sobre el gen: human ... ABCC8(6833) , KCNJ11(3767)

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Glimepiride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:

• Glimepiride Tablets
• Pioglitazone and Glimepiride Tablets

Glimepiride is currently used to treat type 2 diabetes.

Acciones bioquímicas o fisiológicas

Glimepiride is a potent blocker of cardiac K_ATP channels activated by pinacidil with an IC₅₀ of 6.8 nM.

Potent blocker of cardiac K_ATP channels.

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Warning
• Frases de peligro: H361
• Consejos de prudencia: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Clasificaciones de peligro: Repr. 2
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable