Z0153

ZM 241385

≥98% (HPLC), adenosine A2A antagonist, powder

• Sinónimos: 4-(-2-[7-amino-2-{2-furyl}{1,2,4}triazolo{2,3-a} {1,3,5}triazin-5-yl-amino]ethyl)phenol
• Fórmula empírica (notación de Hill): C₁₆H₁₅N₇O₂
• Número CAS: 139180-30-6
• Peso molecular: 337.34
• UNSPSC Code: 12352200
• PubChem Substance ID: 329831597
• NACRES: NA.77
• MDL number: MFCD00908394
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Nombre del producto: ZM 241385, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to tan
• solubility: DMSO: >15 mg/mL
• storage temp.: room temp
• SMILES string: Nc1nc(NCCc2ccc(O)cc2)nc3nc(nn13)-c4ccco4
• InChI: 1S/C16H15N7O2/c17-14-20-15(18-8-7-10-3-5-11(24)6-4-10)21-16-19-13(22-23(14)16)12-2-1-9-25-12/h1-6,9,24H,7-8H2,(H3,17,18,19,20,21,22)
• InChI key: PWTBZOIUWZOPFT-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

ZM 241385 is a potent selective adenosine A2A antagonist.

ZM 241385 is a potent selective adenosine A2A antagonist. The A2A receptor plays a role in regulating myocardial oxygen consumption and coronary blood flow and is highly expressed in the brain, where it has important roles in the regulation of glutamate and dopamine release. ZM 241385 has neuroprotective effects and is being investigated for use in Parkinson′s and other neurodegenerative disorders.

Features and Benefits

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable