T7313

1-[2-(Trifluoromethyl)phenyl]imidazole

• Sinónimos: TRIM
• Fórmula empírica (notación de Hill): C₁₀H₇F₃N₂
• Número CAS: 25371-96-4
• Peso molecular: 212.17
• NACRES: NA.77
• PubChem Substance ID: 24278754
• UNSPSC Code: 12352202
• MDL number: MFCD00041206

Propiedades

• biological source: synthetic (organic)
• Quality Segment: 200
• assay: ≥98% (GC)
• form: solid
• solubility: DMSO: soluble 30 mg/mL
• storage temp.: 2-8°C
• SMILES string: FC(F)(F)c1ccccc1-n2ccnc2
• InChI: 1S/C10H7F3N2/c11-10(12,13)8-3-1-2-4-9(8)15-6-5-14-7-15/h1-7H
• InChI key: WZBWBNCQUTXYEL-UHFFFAOYSA-N
• Gene Information: human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)

Descripción

Biochem/physiol Actions

Potent nitric oxide synthase inhibitor.

Potent nitric oxide synthase inhibitor. Because of the putative involvement of nitric oxide in depression and stress syndromes, TRIM was studied for its antidepressant effects, and found to reduce manifestations of stress in an animal model as well as fluoxetine.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves