T6950

Tizanidine hydrochloride

≥98% (HPLC), powder

• Sinónimos: 5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine hydrochloride
• Fórmula empírica (notación de Hill): C₉H₉Cl₂N₅S
• Número CAS: 64461-82-1
• Peso molecular: 290.17
• NACRES: NA.77
• PubChem Substance ID: 24724634
• UNSPSC Code: 12352200
• MDL number: MFCD00798231
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white
• solubility: H₂O: >20 mg/mL
• originator: Acorda Therapeutics
• SMILES string: Cl[H].Clc1ccc2nsnc2c1NC3=NCCN3
• InChI: 1S/C9H8ClN5S.ClH/c10-5-1-2-6-8(15-16-14-6)7(5)13-9-11-3-4-12-9;/h1-2H,3-4H2,(H2,11,12,13);1H
• InChI key: ZWUKMNZJRDGCTQ-UHFFFAOYSA-N
• Gene Information: human ... ADRA2A(150), ADRA2B(151), ADRA2C(152)

Descripción

Application

Tizanidine hydrochloride has been used for developing spectrophotometric methods for the validation of skeletal muscle relaxants.

Biochem/physiol Actions

α₂-adrenoceptor agonist.

Tizanidine hydrochloride is known to function as a skeletal muscle relaxant that acts centrally. Furthermore, this relaxant functions at spinal and supraspinal levels to block excitatory interneurons. This drug is used for the symptomatic relief of spasticity and painful muscle spasms.

Features and Benefits

This compound was developed by Acorda Therapeutics. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Preparation Note

Tizanidine hydrochloride is soluble in water at a concentration that is greater than 20 mg/ml.

Información de seguridad

• Pictogramas: GHS07
• Palabra de advertencia: Warning
• Códigos de peligro: H302,H315,H319,H335
• Indicaciones de precaución: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos diana: Respiratory system
• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• EPI (equipos de protección individual): dust mask type N95 (US), Eyeshields, Faceshields, Gloves