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T6258

Triosephosphate Isomerase from rabbit muscle

Type X, lyophilized powder, ≥3,500 units/mg protein

Sinónimos:

D-Glyceraldehyde-3-phosphate ketol-isomerase, TPI

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Talla/SKUDisponibilidadPrecio
1 mg

Disponible para enviar HOYdesdeMILWAUKEE

$118,15
5 mg

Fecha estimada de envío06 de octubre de 2026

$468,08

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Número CAS:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-774-2
MDL number:
Número CE:
Specific activity:
≥3,500 units/mg protein

$118,15


Disponible para enviar HOYDetalles


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type

Type X

Quality Segment

form

lyophilized powder

specific activity

≥3,500 units/mg protein

mol wt

calculated mol wt 53.2 kDa

composition

Protein, 60-90% biuret

foreign activity

pyruvate kinase, lactic dehydrogenase, 3-phosphoglyceric phosphokinase, phosphoglucose isomerase, α-glycerophosphate dehydrogenase, aldolase and glyceraldehyde-3-phosphate dehydrogenase ≤0.01%

storage temp.

−20°C

General description

Triosephosphate isomerase (TPI) gene is located on human chromosome 12p13. It is expressed in all tissues. This homodimer of two 27 kDa subunits is highly stable and is made up of 248 amino acids. TPI is catalytically active in its dimeric state.

Application

Triosephosphate isomerase has been used in a study to assess changes in cardiac energy metabolic pathways in overweight rats fed a high-fat diet. Triosephosphate isomerase has also been used in a study to investigate proteomic identification of carbonylated proteins in F344 rat hippocampus after 1-bromopropane exposure.
Triosephosphate Isomerase from rabbit muscle has been complexed with p-hydroxymercurybenzoate (PHMB) to denature the protein for hydrophobic interaction chromatography coupled online with chemical vapour atomic fluorescence spectrometry (HIC−CVGAFS).

Biochem/physiol Actions

Triosephosphate isomerase (TPI) is responsible for the catalysis of the triose phosphate isomers, dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. TPI deficiency is associated with glycolytic enzymopathy. Lack of TPI is also associated with chronic hemolytic anemia, enhanced exposure to bacterial infections, cardiomyopathy and neuromuscular disease.

Packaging

Package size based on protein content

Physical form

Sulfate-free, contains EDTA and borate buffer salts

Other Notes

One unit will convert 1.0 μmole D-glyceraldehyde 3-phosphate to dihydroxyacetone phosphate per min at pH 7.6 at 25 °C.

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Este artículo
T2391A2714A8811
description

Type X, lyophilized powder, ≥3,500 units/mg protein

description

Type III-S, ammonium sulfate suspension, ≥4,000 units/mg protein

description

lyophilized powder, ≥8.0 units/mg protein

description

ammonium sulfate suspension, 10-20 units/mg protein

specific activity

≥3,500 units/mg protein

specific activity

≥4,000 units/mg protein

specific activity

≥8.0 units/mg protein

specific activity

10-20 units/mg protein

form

lyophilized powder

form

ammonium sulfate suspension

form

lyophilized powder

form

ammonium sulfate suspension

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

mol wt

calculated mol wt 53.2 kDa

mol wt

calculated mol wt 53.2 kDa

mol wt

-

mol wt

-

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

200

foreign activity

pyruvate kinase, lactic dehydrogenase, 3-phosphoglyceric phosphokinase, phosphoglucose isomerase, α-glycerophosphate dehydrogenase, aldolase and glyceraldehyde-3-phosphate dehydrogenase ≤0.01%

foreign activity

pyruvate kinase, lactic dehydrogenase, phosphoglucose isomerase, α-glycerophosphate dehydrogenase and aldolase ≤0.001%, glyceraldehyde-3-phosphate dehydrogenase ≤0.01%, 3-phosphoglyceric phosphokinase ≤0.01%

foreign activity

glyceraldehyde-3-phosphate dehydrogenase ≤0.03%, triosephosphate isomerase ≤0.05%, pyruvate kinase ≤0.1%, phosphoglucose isomerase ≤0.6%, lactic dehydrogenase ≤0.03%

foreign activity

glyceraldehyde-3-phosphate dehydrogenase ≤0.03%, phosphoglucose isomerase ≤0.6%, pyruvate kinase ≤0.1%, lactic dehydrogenase ≤0.03%, triosephosphate isomerase ≤0.05%


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Clase de almacenamiento

11 - Combustible Solids

¿Qué está pasando?

WGK 3

Punto de inflamación (°F)

Not applicable

Punto de inflamación (°C)

Not applicable

EPI (equipos de protección individual)

Eyeshields, Gloves, type N95 (US)



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