SRP0315
JARID1A human
recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE)
Sinónimos:
KDM5A, RBP2, lysine (K)-specific demethylase 5A
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.32
biological source
human
recombinant
expressed in baculovirus infected Sf9 cells
assay
≥80% (SDS-PAGE)
form
aqueous solution
mol wt
125 kDa
packaging
pkg of 20 μg
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... KDM5A(5927)
General description
Human JARID1A, also known as KDM5A and RBBP2, (GenBank Accession No. NM_001042603), amino acids 1-1090 with C-terminal FLAG-tag, MW= 125 kDa, expressed in Sf9 cells via a Baculovirus expression system.
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Histone H3 lysine 4 (H3K4) trimethylation (H3K4me3) at the promoter region of genes has been linked to transcriptional activation. In the present study, we found that hypoxia (1% oxygen) increased H3K4me3 in both normal human bronchial epithelial Beas-2B cells and
Alexander Roesch et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 18(9), 1249-1257 (2005-04-02)
In malignant melanomas, the loss of cell cycle control is thought to be due to a lack of retinoblastoma protein (pRb)-activity. Members of the previously described family of retinoblastoma-binding proteins (RBPs) are supposed to act as pRb-modulating factors. Based on
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