SML3579

Pyrimethamine

≥98% (HPLC)

• Sinónimos: 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine, 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine
• Fórmula empírica (notación de Hill): C₁₂H₁₃ClN₄
• Número CAS: 58-14-0
• Peso molecular: 248.71
• UNSPSC Code: 12352116
• NACRES: NA.21
• MDL number: MFCD00057350
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear (Wramed)
• storage temp.: 2-8°C
• SMILES string: Clc1ccc(cc1)c2c(nc(nc2CC)N)N
• InChI: 1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)
• InChI key: WKSAUQYGYAYLPV-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

Antiparasitic inhibitor of dihydrofolate reductase; folic acid antagonist

Pyrimethamine is an antiparasitic drug used to treat malaria, toxoplasmosis and cystoisosporiasis. Pyrimethamine is a potent inhibitor of dihydrofolate reductase.

Información de seguridad

• Pictogramas: GHS07
• Palabra de advertencia: Warning
• Códigos de peligro: H302
• Indicaciones de precaución: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3