SML2929

Bilastine

≥98% (HPLC)

• Sinónimos: 2-[4-(2-(4-(1-(2-ethoxyethyl)benzimidazole-2-yl)piperidine-1-yl)ethyl)phenyl]-2-methyl-propanoic acid, 4-[2-[4-[1-(2-Ethoxyethyl)-1H-benzimidazol-2-yl]-1-piperidinyl]ethyl]-α,α-dimethylbenzeneacetic acid, F-96221-BM1
• Fórmula empírica (notación de Hill): C₂₈H₃₇N₃O₃
• Número CAS: 202189-78-4
• Peso molecular: 463.61
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD09837814
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: [N+H]2(CCC(CC2)c3[n](c4c(n3)cccc4)CCOCC)CCc1ccc(cc1)C(C)(C)C(=O)[O-]
• InChI: 1S/C28H37N3O3/c1-4-34-20-19-31-25-8-6-5-7-24(25)29-26(31)22-14-17-30(18-15-22)16-13-21-9-11-23(12-10-21)28(2,3)27(32)33/h5-12,22H,4,13-20H2,1-3H3,(H,32,33)
• InChI key: ACCMWZWAEFYUGZ-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

Bilastine is an orally available, potent and selective histamine H1 receptor antagonist that exhibits long drug-target residence time at H1 receptor (73 min), which results in extended H1 receptor antagonism in vitro. Bilastine is used for treatment of allergic rhinitis and urticaria (hives).

orally available, potent and selective histamine H1 receptor antagonist that exhibits long drug-target residence time at H1 receptor

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable