SML2546

GLX351322

≥98% (HPLC)

• Sinónimos: 2-[[2-[4-(2-Furanylcarbonyl)-1-piperazinyl]acetyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid ethyl ester
• Fórmula empírica (notación de Hill): C₂₁H₂₅N₃O₅S
• Número CAS: 835598-94-2
• Peso molecular: 431.51
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD05123600
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C(C1=C(NC(CN2CCN(C(C3=CC=CO3)=O)CC2)=O)SC4=C1CCC4)OCC
• InChI key: KEVHLTCEMHIJTQ-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

GLX351322 is a potent and selective inhibitor of NOX4 (NADPH oxidase 4). GLX351322 prevents ROS generation and cellular death, improves pancreatic beta cell function in high-fat diet fed C57Bl/6 mice.

potent and selective inhibitor of NOX4 (NADPH oxidase 4)

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable