SML2114

ZD7155 hydrochloride

≥97% (HPLC)

• Sinónimos: 5,7-Diethyl-3,4-dihydro-1-[[2’-(1H-tetrazol-5-yl)[1,1’-biphenyl]-4-yl]methyl]-1,6-naphthyridin-2(1H)-one hydrochloride, ZD 7155
• Fórmula empírica (notación de Hill): C₂₆H₂₆N₆O · HCl
• Número CAS: 146709-78-6
• Peso molecular: 474.99
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD00921888
• Assay: ≥97% (HPLC)
• Form: powder
• Storage condition: desiccated

Propiedades

• assay: ≥97% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 2 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: CCC1=C(C2=CC(CC)=N1)CCC(N2CC3=CC=C(C=C3)C4=C(C=CC=C4)C5=NN=NN5)=O.Cl
• InChI: 1S/C26H26N6O.ClH/c1-3-19-15-24-22(23(4-2)27-19)13-14-25(33)32(24)16-17-9-11-18(12-10-17)20-7-5-6-8-21(20)26-28-30-31-29-26;/h5-12,15H,3-4,13-14,16H2,1-2H3,(H,28,29,30,31);1H
• InChI key: NAGGAAHTUXEGFG-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

Selective Angiotensin II AT1 antagonist

ZD7155 is a potent selective Angiotensin II AT1 antagonist. In one study ZD 7155 was found to be longer-acting and approximately ten times as potent as losartan in suppressing the angiotensin II-induced pressor response.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3