SML2080

AZD1283

≥98% (HPLC)

• Sinónimos: 6-[4-[[(Benzylsulfonyl)amino]carbonyl]piperidin-1-yl]-5-cyano-2-methylnicotinic acid ethyl ester, Ethyl 5-cyano-2-methyl-6-[4-[[[(phenylmethyl)sulfonyl]amino]carbonyl]-1-piperidinyl]-3-pyridinecarboxylate
• Fórmula empírica (notación de Hill): C₂₃H₂₆N₄O₅S
• Número CAS: 919351-41-0
• Peso molecular: 470.54
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD26395344
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• assay: ≥98% (HPLC)
• form: powder
• color: orange to brown
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: −20°C
• SMILES string: O=C(OCC)C1=CC(C#N)=C(N2CCC(C(NS(CC3=CC=CC=C3)(=O)=O)=O)CC2)N=C1C
• InChI: 1S/C23H26N4O5S/c1-3-32-23(29)20-13-19(14-24)21(25-16(20)2)27-11-9-18(10-12-27)22(28)26-33(30,31)15-17-7-5-4-6-8-17/h4-8,13,18H,3,9-12,15H2,1-2H3,(H,26,28)
• InChI key: NEMHKCNXXRQYRF-UHFFFAOYSA-N

Descripción

Biochem/physiol Actions

AZD1283 is potent non-nucleotide P2Y12 antagonist with a Kd value of 11 nM. It had good antithrombotic activity, inhibiting ADP-induced platelet aggregation. AZD1283 has been used to study the structure of the human P2Y12 receptor.

Potent P2Y12 antagonist with antithrombotic activity

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3