SML1707

Temoporfin

≥90% (HPLC)

• Sinónimos: 3,3′,3′′,3′′′-(7,8-Dihydro-21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-phenol, 5,10,15,20-Tetra(m-hydroxyphenyl)chlorin
• Fórmula empírica (notación de Hill): C₄₄H₃₂N₄O₄
• Número CAS: 122341-38-2
• Peso molecular: 680.75
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥90% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥90% (HPLC)
• form: powder
• color: dark brown to black
• solubility: DMSO: 2 mg/mL, clear (warmed)
• storage temp.: −20°C
• InChI: 1S/C44H32N4O4/c49-29-9-1-5-25(21-29)41-33-13-15-35(45-33)42(26-6-2-10-30(50)22-26)37-17-19-39(47-37)44(28-8-4-12-32(52)24-28)40-20-18-38(48-40)43(36-16-14-34(41)46-36)27-7-3-11-31(51)23-27/h1-17,19,21-24,46-47,49-52H,18,20H2
• InChI key: LYPFDBRUNKHDGX-UHFFFAOYSA-N

Descripción

General description

Temoporfin/(tetra[m-hydroxyphenyl]chlorin, m-THPC), is a hydrophobic second-generation photosensitizer. It is used in the palliative treatment of patients with advanced head and neck cancer by photodynamic therapy.

Biochem/physiol Actions

Temoporfin is a photosensitizer for the photodynamic therapy.

Temoporfin is a photosensitizer for the photodynamic therapy. Temoporfin has been used clinically to treat advanced head and neck squamous cell carcinoma, and is being investigated for use in several other cancers.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable