SML1283

Cilastatin sodium Ready Made Solution

50 mg/mL in DMSO/H₂O, 1:1

• Sinónimos: ((Z)-7-[(2R)-2-Amino-3-hydroxy-3-oxopropyl]sulfanyl-2-{[(1S)-2,2-dimethylcyclopropanecarbonyl]amino}hept-2-enoic acid
• Fórmula empírica (notación de Hill): C₁₆H₂₆N₂O₅S
• Número CAS: 81129-83-1
• Peso molecular: 358.45
• UNSPSC Code: 12352200
• NACRES: NA.77
• Form: liquid (1:1 DMSO:H₂O)

Propiedades

• form: liquid (1:1 DMSO:H₂O)
• Quality Segment: 200
• concentration: 50 mg/mL in DMSO/H₂O, 1:1
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [Na+].S(C[C@@H](N)C(=O)[O-])CCCC\C=C(/NC(=O)[C@@H]1C(C1)(C)C)\C(=O)O
• InChI: 1S/C16H26N2O5S.Na/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21;/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23);/q;+1/p-1/b12-6-;/t10-,11-;/m1./s1
• InChI key: QXPBTTUOVWMPJN-VQAYNFQASA-M

Descripción

Biochem/physiol Actions

Cilastatin sodium is an inhibitor of the renal enzyme dehydropeptidase I and some bacterial zinc-containing β-lactamases.

Cilastatin sodium is an inhibitor of the renal enzyme dehydropeptidase I and some bacterial zinc-containing β-lactamases. By this action, cilastatin suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy.

Información de seguridad

• Clase de almacenamiento: 10 - Combustible liquids
• wgk: WGK 3
• flash_point_f: 188.6 °F - closed cup
• flash_point_c: 87 °C - closed cup