SMB00436

Pinoresinol diglucoside

≥98% (HPLC)

• Sinónimos: (+)-Pinoresinol 4,4′-O-bisglucopyranoside, Pinoresinol di-β-D-glucoside
• Fórmula empírica (notación de Hill): C₃₂H₄₂O₁₆
• Número de CAS: 63902-38-5
• Peso molecular: 682.67
• Número MDL: MFCD06656077
• Código UNSPSC: 12352205
• ID de la sustancia en PubChem: 329825015
• NACRES: NA.25

Propiedades

• Nivel de calidad: 200
• Ensayo: ≥98% (HPLC)
• Formulario: powder
• aplicaciones: metabolomics; vitamins, nutraceuticals, and natural products
• temp. de almacenamiento: −20°C
• cadena SMILES: O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](OC2=CC=C([C@H]3OC[C@@]4([H])[C@]3([H])CO[C@@H]4C5=CC=C(O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C(OC)=C5)C=C2OC)[C@@H]1O
• InChI: 1S/C32H42O16/c1-41-19-7-13(3-5-17(19)45-31-27(39)25(37)23(35)21(9-33)47-31)29-15-11-44-30(16(15)12-43-29)14-4-6-18(20(8-14)42-2)46-32-28(40)26(38)24(36)22(10-34)48-32/h3-8,15-16,21-40H,9-12H2,1-2H3/t15-,16-,21+,22+,23+,24+,25-,26-,27+,28+,29+,30+,31+,32+/m0/s1
• Clave InChI: ZJSJQWDXAYNLNS-FUPWJLLWSA-N

Descripción

Descripción general

Pinoresinol diglucoside (PDG) is an important lignan found in the bark of the traditional Chinese medicinal plant Eucommia ulmoides, also known as Tu-Chung. It is also associated with other plants such as Forsythia suspensa and Styrax spp. In plants, PDG is produced through the phenylpropanoid pathway.

Pinoresinol diglucoside is an important lignan found in the bark of the Eucommia ulmoides, which is known in traditional Chinese medicine as du zhong.[1] In plants, pinoresinol diglucoside is produced through the phenylpropanoid pathway.[2]

Acciones bioquímicas o fisiológicas

Pinoresinol diglucoside has antihypertensive properties.[1] It serves as a α-glucosidase inhibitor. α-Glucosidase catalyzes the conversion of carbohydrates to glucose in the small intestine. Hence, pinoresinol diglucoside might be useful as an antidiabetic agent.[3]

Pinoresinol diglucoside is a potent antihypertensive, anti-inflammatory and antioxidant agent. It also exerts tumor-suppressive and anti-osteoporotic properties. PDG serves as an α-glucosidase inhibitor that catalyzes the conversion of carbohydrates to glucose in the small intestine. Hence, it may serve as an antidiabetic agent in the management of diabetes. It displays neuroprotective properties by alleviating ischemic stroke-related brain injury in mice model.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable