SAE0004

Kynurenine 3-Monooxygenase, Pseudomonas fluorescens (strain 17400), Recombinant

• Sinónimos: KMO
• Número CE: 1.14.13.9 (BRENDA, IUBMB)
• NACRES: NA.54
• UNSPSC Code: 12352204
• Specific activity: ≥3 U/mg

Propiedades

• form: solution
• Quality Segment: 200
• specific activity: ≥3 U/mg
• mol wt: 50,712 Da
• shipped in: dry ice
• storage temp.: −70°C

Descripción

General description

Kynurenine 3-monooxygenase (KMO) is a flavoprotein aromatic hydroxylase (FAH) that catalyzes the hydroxylation of L-kynurenine (L-Kyn) to produce 3-hydroxykynurenine (3-OH-Kyn). This activity is central to tryptophan metabolism and also to the production of nicotinamide adenine dinucleotide (NAD) in higher organisms. KMO contains flavin adenine dinucleotide (FAD) as a non-covalent, but tightly bound, co-factor at a 1:1 ratio of co-factor to protein.

Other Notes

1 unit will oxidize L-kynurenine at 1 mol/min at pH 7.0, 25°C.

Información de seguridad

• Clase de almacenamiento: 12 - Non Combustible Liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable