G1/S-specific cyclin-E1 (Cyclin E) is a regulatory subunit of CDK2 during G1 phase and controls G1/S transition during the mammalian cell cycle. The Cyclin E/CDK2 complex phosphorylates p27Kip1 and truncated variant isoforms of cyclin E can phosphorylate histone H1 to initiate DNA synthesis. Multiple isoforms of cyclin E are identified in tumor tissues.
Inmunógeno
Near the C-terminus of the human cyclin E1 protein.
Características y beneficios
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Forma física
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
¿No encuentra el producto adecuado?
Pruebe nuestro Herramienta de selección de productos.
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
