SAB4503999

Anti-phospho-TIE2 (pTyr¹¹⁰⁸) antibody produced in rabbit

affinity isolated antibody

• Sinónimos: Anti-CD202B, Anti-GLC3E, Anti-TIE-2, Anti-VMCM, Anti-VMCM1
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: antigen 125 kDa
• reactividad de especies: mouse, rat, human
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:10000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• Nº de acceso NCBI: Q02763
• Nº de acceso UniProt: Q02763
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: phosphorylation (pTyr1108)
• Información sobre el gen: human ... TEK(7010)

Descripción

Descripción general

The TIE2 (TEK receptor tyrosine kinase) is also termed as TEK (tyrosine-protein kinase receptor). This gene is located on human chromosome 9p21.2. It is expressed in the Schlemm′s canal endothelial of the eye. TIE2 belongs to the receptor tyrosine kinases family.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human TIE2 around the phosphorylation site of Tyr1108.

Immunogen Range: 1074-1123

Acciones bioquímicas o fisiológicas

Tie-2 (TEK receptor tyrosine kinase) protein induces angiogenesis and supports endothelial cell survival, upon binding of angiopoietin-1 (an endothelial growth factor) to the receptor. This gene is necessary for Schlemm′s canal formation. This gene regulates vascular homeostasis by involving in auto or transphosphorylation. Tie-2 is essential for the growth of vascular structures during embryogenesis.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable