SAB4501939

Anti-B-MYB antibody produced in rabbit

affinity isolated antibody

• Sinónimos: BMYB, MYBB, MYBL2, Myb-related protein B
• UNSPSC Code: 12352203
• NACRES: NA.41

Propiedades

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 79 kDa
• species reactivity: mouse, human, rat
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:20000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• NCBI accession no.: P10244
• UniProt accession no.: P10244
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... MYBL2(4605)

Descripción

General description

MYB proto-oncogene like 2/v-myb avian myeloblastosis viral oncogene homolog-like 2 (MYBL2/B-MYB) belongs to the MYB family of transcription factors. MYBL2 gene is located on human chromosome 20q13.

Immunogen

The antiserum was produced against synthesized peptide derived from human B-Myb.

Immunogen Range: 551-600

Biochem/physiol Actions

MYB proto-oncogene like 2/v-myb avian myeloblastosis viral oncogene homolog-like 2 (MYBL2/B-MYB) protein regulates cell proliferation, differentiation, and DNA repair. It participates in DNA replication in embryonic stem cells. MYBL2 protein can modulate stem cell genes. MYBL2 gene expression is altered in breast, ovarian, liver, colon, rectal, blood, brain, and bladder cancers. MYBL2 affects cell cycle progression and apoptosis in a regulated manner. It serves as a cell cycle modulator in hepatocellular carcinoma (HCC).

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable