Anti-CNR1 Antibody detects endogenous levels of total CNR1 protein.
CNR1 (cannabinoid receptor 1) is a member of the class A G protein-coupled receptor (GPCR) family. It is also known as the type-1 cannabinoid receptor (CB1). It is expressed at high level in the brain and the central nervous system. It is located on human chromosome 6q15.
Immunogen
The antiserum was produced against synthesized peptide derived from human CNR1.
Immunogen Range: 151-200
Biochem/physiol Actions
CNR1 (cannabinoid receptor 1) participates in most of the activities of the brain and body. It is sensitive to hebephrenic schizophrenia. Experimental studies hypothesize that aberrations in CNR1 gene increases the risk of susceptibility to substance abuse.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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The incentive salience of alcohol: translating the effects of genetic variant in CNR1.
Hutchison KE, et al.
Archives of General Psychiatry, 65(7), 841-850 (2008)
Cannabinoid receptor gene (CNR1): association with iv drug use.
Comings DE, et al.
Molecular Psychiatry, 2(2), 161-161 (1997)
CNR1, central cannabinoid receptor gene, associated with susceptibility to hebephrenic schizophrenia.
Ujike H, et al.
Molecular Psychiatry, 7(5), 515-515 (2002)
The CB1 receptor as the cornerstone of exostasis.
Piazza PV, et al.
Neuron, 93(6), 1252-1274 (2017)
Crystal structure of the human cannabinoid receptor CB 1.
Hua T, et al.
Cell, 167(3), 750-762 (2016)
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