S0375

D-Saccharic acid 1,4-lactone monohydrate

≥98.0% (HPLC)

• Sinónimos: D-Glucaric acid-1,4-lactone, D-Saccharolactone
• Fórmula empírica (notación de Hill): C₆H₈O₇ · H₂O
• Número de CAS: 61278-30-6
• Peso molecular: 210.14
• Beilstein: 85594
• Número MDL: MFCD00149334
• Código UNSPSC: 12352201
• ID de la sustancia en PubChem: 24899420
• NACRES: NA.25

Propiedades

• Nivel de calidad: 200
• Ensayo: ≥98.0% (HPLC)
• Formulario: powder
• impurezas: ≤10.0% water (Karl Fischer)
• color: white
• mp: 91 - 93 °C ((196 - 199 °F ))
• solubilidad: water: 50 mg/mL, clear, colorless to faintly yellow
• temp. de almacenamiento: 2-8°C
• cadena SMILES: O.O[C@@H]1[C@@H](O)C(=O)O[C@@H]1[C@H](O)C(O)=O
• InChI: 1S/C6H8O7.H2O/c7-1-2(8)6(12)13-4(1)3(9)5(10)11;/h1-4,7-9H,(H,10,11);1H2/t1-,2-,3+,4+;/m1./s1
• Clave InChI: NPFKVZHSFSFLPU-QGBSHYGGSA-N

Descripción

Descripción general

D-Saccharic acid 1,4-lactone monohydrate (DSAL) has an ability to inhibit the activity of β-glucuronidase enzyme.[1]It also potentially inhibits Klotho deglycosylation of excitatory amino acid transporters (EAATs) and peptide transporters (PEPTs).[2]

Aplicación

D-Saccharic acid 1,4-lactone monohydrate has been used as a constituent of phosphate buffer to block incidental β-glucuronidase activity in Streptococcus pneumoniae hyaluronan lyase (SpnHL) activity assay.[3] It has also been used as a component of reaction mixture in Iduronidase activity assay[4] and UDP-glucuronosyltransferase 1 (UGT1A1) inhibition assay.[5]

Otras notas

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)