P8013

Pargyline hydrochloride

synthetic, 98% (TLC), MAO-B inhibitor, powder or crystals

• Sinónimos: N-Methyl-N-(2-propynyl)benzylamine hydrochloride, N-Methyl-N-propargylbenzylamine hydrochloride
• Fórmula lineal: C₆H₅CH₂N(CH₃)CH₂C≡CH·HCl
• Número CAS: 306-07-0
• Peso molecular: 195.69
• NACRES: NA.77
• PubChem Substance ID: 24278153
• UNSPSC Code: 12352200
• EC Number: 206-175-1
• MDL number: MFCD00012492
• Beilstein/REAXYS Number: 3699487
• Assay: 98% (TLC)
• Form: powder or crystals

Propiedades

• Nombre del producto: Pargyline hydrochloride,
• biological source: synthetic
• Quality Segment: 200
• assay: 98% (TLC)
• form: powder or crystals
• mp: 160-163 °C (lit.)
• solubility: water: 50 mg/mL, clear, colorless to faintly yellow
• storage temp.: −20°C
• SMILES string: Cl[H].CN(CC#C)Cc1ccccc1
• InChI: 1S/C11H13N.ClH/c1-3-9-12(2)10-11-7-5-4-6-8-11;/h1,4-8H,9-10H2,2H3;1H
• InChI key: BCXCABRDBBWWGY-UHFFFAOYSA-N
• Gene Information: human ... MAOA(4128), MAOB(4129)

Descripción

Application

Pargyline hydrochloride has been used:

• as a histone demethylase inhibitor to treat monocytes to investigate whether various inhibitors affect training
• to maximize uptake into dopaminergic neurons (DA) neurons in experimental rats,
• to study its effect on discolouration of medullary tissues of sclerotia of S. sclerotiorum

Biochem/physiol Actions

Pargyline hydrochloride acts as a histone demethylase inhibitor. It has antihypertensive action.

Selective MAO-B inhibitor.

Información de seguridad

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves