P7547

Phentolamine hydrochloride

≥98% (TLC), α-adrenoceptor antagonist, powder

• Sinónimos: 2-[N-(3-Hydroxyphenyl)-p-toluidinomethyl]-2-imidazolidine hydrochloride, 3-[[(4,5-Dihydro-1H-imidazol-2-yl)-methyl](4-methylphenyl)-amino]-phenol monohydrochloride
• Fórmula empírica (notación de Hill): C₁₇H₁₉N₃O · HCl
• Número CAS: 73-05-2
• Peso molecular: 317.81
• NACRES: NA.77
• PubChem Substance ID: 24898856
• UNSPSC Code: 12352116
• EC Number: 200-793-5
• MDL number: MFCD00079268
• Beilstein/REAXYS Number: 3764617
• Assay: ≥98% (TLC)
• Form: powder

Propiedades

• Nombre del producto: Phentolamine hydrochloride, ≥98% (TLC), powder
• Quality Segment: 200
• assay: ≥98% (TLC)
• form: powder
• color: white to off-white
• solubility: ethanol: 14 mg/mL, H₂O: 20 mg/mL, H₂O: unstable (prepare immediately prior to use)
• originator: Novartis
• SMILES string: Cl[H].Cc1ccc(cc1)N(CC2=NCCN2)c3cccc(O)c3
• InChI: 1S/C17H19N3O.ClH/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H
• InChI key: TUEJFGFQYKDAPM-UHFFFAOYSA-N
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)

Descripción

Biochem/physiol Actions

α-adrenoceptor antagonist; peripheral vasodilator.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Preparation Note

Protect From Light.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves