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Merck

O5632

Linoleic acid, conjugated methyl ester

Sinónimos:

CLA methyl ester, Octadecadienoic acid, conjugated, methyl ester

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NACRES:
NA.25
UNSPSC Code:
12352211
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biological source

plant (safflower)

Quality Segment

assay

≥99% (GC)

form

liquid

technique(s)

GC/MS: suitable, HPLC: suitable

impurities

≤1% Linoleic acid methyl ester

functional group

carboxylic acid, ester

lipid type

omega FAs

shipped in

ambient

storage temp.

−20°C

General description

Conjugated linoleic acid (CLA) describes the positional and geometric isomers of C18:2 fatty acids (FA) with a conjugated double bond. cis-9, trans-11 CLA are considered as the major isomers of CLA, based on in vitro experiments and animal studies in milk. The major source of CLA in human diet is the ruminant fat.

Application

Linoleic acid, conjugated methyl ester (CLA) has been used as a standard for the determination of isomers of CLA in milk samples by high performance liquid chromatography (HPLC), gas chromatography-mass spectrometry. It has also been used in the production of sn-1,3 diacyl glycerol.

Biochem/physiol Actions

Conjugated linoleic acid (CLA) isomers as supplements inhibit the growth of numerous human cancer cell lines. It also possesses immunostimulant properties, prevents diabetes and reduces atherosclerosis.

Other Notes

A mixture of cis- and trans-9,11- and -10,12-octadecadienoic acid methyl esters. Isomer ratio may vary from lot to lot.


Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves



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