N7510

Nicardipine hydrochloride

≥98%, L-type voltage-dependent calcium channel blocker, powder

• Sinónimos: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 2-[methyl(phenylmethyl)amino]ethyl ester hydrochloride, YC-93
• Fórmula empírica (notación de Hill): C₂₆H₂₉N₃O₆ · HCl
• Número CAS: 54527-84-3
• Peso molecular: 515.99
• NACRES: NA.77
• PubChem Substance ID: 24277856
• UNSPSC Code: 12352200
• EC Number: 259-198-4
• MDL number: MFCD00057327
• Assay: ≥98%
• Form: powder

Propiedades

• Nombre del producto: Nicardipine hydrochloride, powder, ≥98%
• Quality Segment: 100
• assay: ≥98%
• form: powder
• color: yellow
• solubility: DMSO: ~1 mg/mL, 0.1 M NaOH: insoluble, H₂O: slightly soluble, methanol: soluble
• originator: EKR Therapeutics
• storage temp.: 2-8°C
• SMILES string: Cl[H].COC(=O)C1=C(C)NC(C)=C(C1c2cccc(c2)[N+]([O-])=O)C(=O)OCCN(C)Cc3ccccc3
• InChI: 1S/C26H29N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15,24,27H,13-14,16H2,1-4H3;1H
• InChI key: AIKVCUNQWYTVTO-UHFFFAOYSA-N
• Gene Information: human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779)

Descripción

Biochem/physiol Actions

Blocks L-type voltage-dependent calcium channels; antihypertensive.

Features and Benefits

This compound was developed by EKR Therapeutics. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• pictograms: GHS06
• signalword: Danger
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• hcodes: H301
• pcodes: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral