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Merck

M8770

Sigma-Aldrich

Anti-Mouse IgG1 (heavy chain specific) antibody produced in goat

affinity isolated antibody, lyophilized powder

Sinónimos:

Anti-Mouse Igg1, Heavy Chain Specific Secondary Antibody, Heavy Chain Specific Secondary Antibody - Anti-Mouse IgG1 (heavy chain specific) antibody produced in goat

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About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.46

origen biológico

goat

Nivel de calidad

200
300

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

secondary antibodies

clon

polyclonal

Formulario

lyophilized powder

técnicas

Ouchterlony double diffusion: suitable

temp. de almacenamiento

2-8°C

modificación del objetivo postraduccional

unmodified

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Descripción general

Immunoglobulin IgG is a glycoprotein antibody with two light chains and a pair of identical heavy chains.

Inmunógeno

Mouse IgG1 (myeloma protein)

Aplicación

Anti-Mouse IgG1 (heavy chain specific) antibody is suitable for use in immunoelectrophoresis and Ouchterlony double diffusion. The antibody may also be used in immunoblot .
Anti-Mouse IgG1 (heavy chain specific) antibody produced in goat has been used in immunohistochemistry and enzyme-linked immunosorbent assay (ELISA)

Acciones bioquímicas o fisiológicas

Digestion of IgG by papain results in the generation of fragment antigen-binding (Fab). Pepsin digestion of IgG results in fragment crystallizable (fc). IgG1 is most abundant of IgG types and its deficiency results in hypogammaglobulinemia.

Forma física

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2.

Reconstitución

Reconstitute with 0.135 M sodium chloride.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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A H Schrijvers et al.
Cancer research, 53(18), 4383-4390 (1993-09-15)
Using viable cells of a human head and neck squamous cell carcinoma (HNSCC) cell line as immunogen, we developed monoclonal antibody (MAb) U36. Immunohistochemical examination revealed distinct surface labeling of MAb U36 with normal human squamous epithelium and squamous cell
The combined effect of mesenchymal stem cells and resveratrol on type 1 diabetic neuropathy
Wang C, et al.
Experimental and Therapeutic Medicine, 17(5), 3555-3563 (2019)
J Pass et al.
Scandinavian journal of immunology, 58(3), 298-305 (2003-09-03)
The urokinase receptor (uPAR) is a glycolipid-anchored cell surface glycoprotein that plays a central role in extracellular proteolysis during tissue remodeling processes including cancer invasion. Furthermore, uPAR is found on the surface of both dendritic cells (DCs) and T cells
Min-Kyung Sung et al.
Molecular biology of the cell, 27(17), 2642-2652 (2016-07-08)
Ribosome assembly is an essential process that consumes prodigious quantities of cellular resources. Ribosomal proteins cannot be overproduced in Saccharomyces cerevisiae because the excess proteins are rapidly degraded. However, the responsible quality control (QC) mechanisms remain poorly characterized. Here we
Min-Kyung Sung et al.
eLife, 5 (2016-08-24)
Overproduced yeast ribosomal protein (RP) Rpl26 fails to assemble into ribosomes and is degraded in the nucleus/nucleolus by a ubiquitin-proteasome system quality control pathway comprising the E2 enzymes Ubc4/Ubc5 and the ubiquitin ligase Tom1. tom1 cells show reduced ubiquitination of

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