M5391

(±)-Metoprolol (+)-tartrate salt

≥98% (titration), powder

• Sinónimos: Lopressor
• Fórmula lineal: (C₁₅H₂₅NO₃)₂ · C₄H₆O₆
• Número de CAS: 56392-17-7
• Peso molecular: 684.81
• Número CE: 260-148-9
• Número MDL: MFCD00056257
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 24278556
• NACRES: NA.77

Propiedades

• Ensayo: ≥98% (titration)
• Formulario: powder
• color: white to off-white
• solubilidad: H₂O: 50 mg/mL
• emisor: Novartis
• cadena SMILES: O[C@H]([C@@H](O)C(O)=O)C(O)=O.COCCc1ccc(OCC(O)CNC(C)C)cc1.COCCc2ccc(OCC(O)CNC(C)C)cc2
• InChI: 1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..1/s1
• Clave InChI: YGULWPYYGQCFMP-CEAXSRTFSA-N
• Información sobre el gen: human ... ADRB1(153)

Descripción

Descripción general

Metoprolol has antihypertensive and anti-ischemic properties. It is used to treat arrhythmias.

Aplicación

(±)-Metoprolol (+)-tartrate salt has been used:

• to modulate the immunological parameters in various studies
• to study its effects onCa²⁺-calmodulin-dependent protein kinase II (CaMKII) activity in human and experimental heart failure (HF)
• to examine the contribution of the adrenergic receptors to the production of norepinephrine (NE)-mediated O^2-

Acciones bioquímicas o fisiológicas

β₁-adrenoceptor antagonist.

Características y beneficios

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Otras notas

Shelf-life of the powder is at least 4 years.

Información de seguridad

• Pictogramas: GHS08,GHS09
• Palabra de señalización: Warning
• Frases de peligro: H361d,H411
• Consejos de prudencia: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Clasificaciones de peligro: Aquatic Chronic 2 - Repr. 2
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)